Package: KinformR
Title: Relationship-Informed Pedigree and Variant Scoring
Version: 0.1.2
Authors@R: 
    person("Cameron M.", "Nugent", , "cam.nugent@sequencebio.com", role = c("aut", "cre"),
           comment = c(ORCID = "0000-0002-1135-2605"))
Maintainer: Cameron M. Nugent <cam.nugent@sequencebio.com>
Description: Comparative evaluation of families and candidate variants
        in rare-variant association studies. The package can be used
        for two methodologically overlapping but distinct purposes.
        First, the prior to any genetic or genomic evaluation,
        evaluation of relative detection power of pedigrees, can direct
        recruitment efforts by showing which individuals not yet
        sampled would be the most meaningful additions to a study.
        Second, after sequencing and analysis, variants based on
        association with disease status and familial relationships of
        individuals, aids in variant prioritization. Methodology is
        described in Nugent (2025) <doi:10.1101/2025.10.06.25337426>.
License: MIT + file LICENSE
URL: https://github.com/SequenceBio/KinformR
BugReports: https://github.com/SequenceBio/KinformR/issues
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
VignetteBuilder: knitr
Suggests: devtools, testthat, knitr, rmarkdown
Repository: https://sequencebio.r-universe.dev
Date/Publication: 2026-02-17 19:37:44 UTC
RemoteUrl: https://github.com/sequencebio/kinformr
RemoteRef: HEAD
RemoteSha: f1846392469c763d87305fb82cba41282ee688bf
NeedsCompilation: no
Packaged: 2026-10-16 07:27:36 UTC; root
Author: Cameron M. Nugent [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-1135-2605>)